10 Best Supplements for Weight Loss and Muscle Gain (2025)
Reading Time: 13 minutes If you are one of those lucky people who need to both gain muscle and lose weight (primarily fat, I’m assuming), then you can be happy you found my website.
My list of the best supplements for muscle gain and weight loss includes only five supplements, but it is a weight loss and muscle gain supplement stack that I am confident will produce results.
My name is Adam Kemp, and I am a professional basketball who has spent their whole career (10+ years of professional basketball and still going) trying to gain muscle and lose weight.
As a 6′ 10″ center who grew up with asthma and a naturally chubby body, learning how to improve my body composition has been one of the keys to the length of my career.
Additionally, while completing my Masters’s Degree in Nutrition Education at American University, I extensively studied supplements for athletic performance, body composition change, and improved general health.
My diverse background in fitness and nutrition has given me an edge in understanding the best strategies and products for weight loss and muscle gain.
So, you can believe me when I say these supplements are game-changers.
If you want to lose fat and gain muscle at the same time, you are going to need to do more than a few things correctly.
By incorporating these ten supplements into your routine, you’ll fuel your body with the nutrients needed to optimize muscle growth, accelerate fat loss, and unlock your best body composition.
Top 10 Supplements for Muscle Gain & Weight Loss
One of the primary advantages of using the supplement stack I am suggesting is the convenience it offers.
Instead of spending countless hours researching and purchasing individual products, you can rely on this carefully curated stack to cover your bases, streamlining your journey toward weight loss and muscle gain.
I understand some people may have concerns or doubts about using supplements for weight loss and muscle gain because of the supplement industry’s reputation.
However, the supplements I recommend are backed by scientific research.
If you’re serious about building muscle and losing fat, investing in this supplement stack will give you the edge you need to reach your goals faster and more efficiently.
By incorporating scientifically backed ingredients like protein, amino acids, probiotics, and natural metabolism boosters, you can create the best supplement stack for cutting that enhances the body’s ability to burn fat, improve digestion, and sustain long-term weight management while also helping boost your workouts and build strength and lean muscle.
Read below to learn how these supplements can help you build muscle and lost weight:
1.) Garden of Life Raw Organic Protein & Greens
If you want to lose weight and build muscle, I believe Garden of Life Organic Protein and Greens is the first supplement you should buy.
Garden of Life Protein & Greens is the best supplement for helping you build muscle and burn fat because it provides 20 grams of protein to stimulate your metabolism and keep you feeling full, along with digestive enzymes and probiotics that support a healthy gut microbiome.
Each serving of this vegan protein powder supplement provides 20 grams of clean, organic protein from sources like peas, sprouted brown rice, and lentils, as well as a blend of organic greens, including spinach, kale, and broccoli, that are rich in essential vitamins and minerals.
Consuming adequate protein can help promote muscle gain and reduce muscle breakdown, making it a must-have for anyone looking to improve their body composition by building muscle.
The added greens in this supplement also offer numerous benefits for overall health and weight management. Greens are low in calories but high in fiber, which can help you feel full and satisfied, reducing the likelihood of overeating.
They also provide essential micronutrients that support immune function, energy production, and overall well-being.
But that’s not all.
Garden of Life Organic Protein & Greens also contains a probiotic blend with over 1 billion CFUs (colony-forming units) of beneficial probiotic bacteria per serving, including strains like Lactobacillus acidophilus and Bifidobacterium lactis.
Probiotics are live microorganisms that provide a range of health benefits, such as supporting digestive health by promoting the growth of healthy gut bacteria and improving the balance of the gut microbiome.
Adding probiotics to a protein and greens supplement can provide additional health benefits, making Garden of Life Organic Protein & Greens a great choice for supporting overall health and wellness.
Furthermore, this supplement is made from organic and raw ingredients, ensuring optimal nutrient absorption and minimal processing.
For these reasons, I believe Garden of Life Protein & Greens is one of the best supplements for losing weight and gaining muscle.
Research supports the use consumption of protein powder both before and after workouts to maximize the development of lean muscle mass and the reduction of body fat mass. To get the best results, I suggest you drink one scoop of Garden of Life Raw Organic Protein & Greens about 45 minutes before training and another about 30 minutes after finishing your workouts.
Last update on 2025-04-19 / This article includes affiliate links/Images via Amazon Product Advertising API. I may earn commissions on purchases made through these links.
2.) RSP Amino Lean
RSP Amino Lean is an all-in-one solution for building muscle and losing weight.
This versatile supplement contains a blend of essential amino acids (EAAs) and branched-chain amino acids (BCAAs), which play a crucial role in muscle growth and recovery.
EAAs and BCAAs help stimulate protein synthesis, reduce muscle breakdown, and promote muscle repair.
In addition to amino acids, RSP Amino Lean contains a weight loss blend that features ingredients like conjugated linoleic acid (CLA) and green tea extract.
CLA is a natural fatty acid that has been shown to promote fat loss and support lean muscle mass, while green tea extract contains potent antioxidants called catechins that have been linked to increased fat oxidation and improved metabolism.
By supporting workout performance, enhancing recovery, and promoting fat loss, RSP Amino Lean can help you burn fat and build muscle quickly.
Drink one or two servings of AminoLean and go for a walk before eating anything. By consuming the fat-burning matrix and amino acids in Amino Lean on an empty stomach and then doing some low-intensity cardio, your body can preferentially burn fat while having an adequate fuel source to avoid muscle wasting.
Last update on 2025-04-20 / This article includes affiliate links/Images via Amazon Product Advertising API. I may earn commissions on purchases made through these links.
3.) Optimum Nutrition Gold Standard Pre-Workout
Optimum Nutrition Gold Standard Pre-Workout is my favorite pre workout supplements one of the best supplements for weight loss and muscle building because it is a powerful supplement designed to help you get the most out of your workouts.
By taking one serving of Optimum Nutrition Gold Standard Pre Workout before your workouts, you will exercise longer and more intensely, and you will get an aesthetic body faster.
Key ingredients in ON Gold Standard Pre Workout include caffeine, creatine, citrulline, and beta-alanine, which boost energy, focus, and endurance.
Caffeine is a well-known stimulant that can help increase alertness and reduce perceived exertion during exercise, allowing you to push harder and longer in your workouts.
Creatine monohydrate is a natural compound that helps supply energy to your muscles, improving strength and power output.
Beta-alanine is an amino acid that helps buffer muscle acidity, delaying the onset of muscle fatigue and allowing for more intense training sessions.
Citrulline malate is an amino acid compound that can enhance exercise performance by increasing blood flow and reducing muscle fatigue.
Along with improving your workouts, this Optimum Nutrition Pre Workout can help you build muscle and lose weight by increasing muscle protein synthesis, which is the process by which new muscle tissue is formed.
This effect is attributed to the presence of creatine in the formula, which stimulates protein synthesis and promotes muscle growth.
Furthermore, the caffeine content in Optimum Nutrition Gold Standard Pre-Workout can increase metabolic rate, leading to more calories burned during exercise and even after the workout is over.
This thermogenic effect can contribute to weight loss, especially when combined with a healthy diet and regular exercise.
Overall, Optimum Nutrition Gold Standard Pre-Workout is an excellent supplement for those looking to improve their workout performance, build muscle, and lose weight.
Use Optimum Nutrition Gold Standard Pre-Workout consistently to receive the benefits of long-term creatine monohydrate and beta-alanine consumption.
Both of these nutrients “load” in your body and consuming them becomes more effective over time.
Try consuming Optimum Nutrition Gold Standard Pre-Workout consistently for at least two months to see the best results.
Last update on 2025-04-20 / This article includes affiliate links/Images via Amazon Product Advertising API. I may earn commissions on purchases made through these links.
4.) Naturewise Turmeric
Using turmeric for weight loss is effective because chronic inflammation can hinder muscle recovery and growth and reduce your metabolic rate.
By potentially reducing chronic inflammation, this turmeric supplement may help promote faster muscle recovery and support muscle growth, contributing to overall weight loss and muscle gain.
This means that your body can absorb and utilize more of the active compounds found in turmeric, making the supplement more effective at mitigating inflammation and supporting muscle recovery.
This could indirectly contribute to weight loss by helping you build more muscle mass, which in turn can boost your metabolism and help you burn more calories.
White turmeric, one of the supplement’s key ingredients, is known for its role in maintaining healthy stress levels and promoting digestive health.
A well-functioning digestive system ensures that your body can effectively break down and use the nutrients you consume, which is essential for muscle growth and fat loss.
Furthermore, managing stress is crucial in a weight loss and muscle gain journey as it can help prevent emotional eating and promote better sleep, both of which can contribute to your fitness goals.
Therefore, it aligns well with clean eating habits that often accompany fitness routines focused on weight loss and muscle gain.
Last update on 2025-04-20 / This article includes affiliate links/Images via Amazon Product Advertising API. I may earn commissions on purchases made through these links.
5.) Bloom Greens & Superfoods Powder
Bloom Greens & Superfoods Powder is a powerful supplement designed to enhance digestion, optimize nutrient absorption, and support metabolism.
A well-functioning digestive system is essential for both losing fat and building muscle, as it allows the body to efficiently process and utilize nutrients from food.
This formula contains a blend of probiotics, prebiotics, and digestive enzymes, all of which play a critical role in improving gut health and boosting energy levels.
A balanced gut microbiome enhances digestion, regulates inflammation, and promotes the absorption of key nutrients necessary for muscle repair and growth.
The fiber content in Bloom Greens helps maintain regular digestion and stabilizes blood sugar levels, reducing cravings and preventing energy crashes.
Digestive enzymes further assist in breaking down proteins, carbohydrates, and fats, allowing the body to utilize these nutrients effectively for muscle recovery and fat metabolism.
By supporting digestion and reducing inflammation, Bloom Greens & Superfoods Powder helps create an optimal internal environment for sustainable weight management and lean muscle development.
- Enhances nutrient absorption to fuel muscle growth
- Improves digestion and reduces bloating for better metabolism
- Supports natural detoxification, helping the body burn fat more efficiently
Last update on 2025-04-19 / This article includes affiliate links/Images via Amazon Product Advertising API. I may earn commissions on purchases made through these links.
6.) Force Factor Colostrum
Force Factor Colostrum is a powerful supplement that enhances digestion, supports immune function, and optimizes metabolic efficiency, making it a valuable tool for both fat loss and muscle building.
Derived from bovine colostrum, this supplement is packed with immunoglobulins, lactoferrin, and growth factors that aid in gut health, cellular repair, and nutrient absorption.
A well-functioning gut is essential for maximizing muscle growth and promoting fat metabolism.
Colostrum helps strengthen the gut lining, reduce inflammation, and create a balanced microbiome, all of which contribute to improved digestion and metabolic health.
A healthy gut ensures the body efficiently absorbs essential nutrients like protein and amino acids needed for muscle repair, while also regulating insulin sensitivity and fat storage.
Research suggests that when combined with exercise, colostrum supplementation can promote lean muscle mass while supporting fat loss.
Studies indicate that individuals consuming colostrum supplements alongside aerobic and resistance training experience increased muscle retention and improved metabolic function, likely due to colostrum’s role in nutrient utilization and immune support.
By improving digestion, reducing inflammation, and enhancing nutrient absorption, Force Factor Colostrum helps create an ideal environment for muscle growth while also supporting efficient fat metabolism.
- Strengthens the gut lining to improve digestion and nutrient absorption
- Reduces inflammation, promoting muscle recovery and fat loss
- Supports immune function, optimizing overall metabolic health
Last update on 2025-04-20 / This article includes affiliate links/Images via Amazon Product Advertising API. I may earn commissions on purchases made through these links.
7.) Xtend Ripped
Xtend Ripped is a branched-chain amino acid (BCAA) supplement designed to optimize fat metabolism, preserve muscle mass, and support exercise recovery.
It provides essential nutrients that help the body utilize fat as an energy source while maintaining lean muscle, making it an excellent choice for those looking to improve body composition.
BCAAs play a critical role in muscle repair and recovery, helping to reduce soreness and prevent muscle breakdown during calorie restriction or intense training.
Preserving muscle mass is essential for maintaining a high metabolic rate, as muscle tissue burns more calories at rest than fat.
By ensuring muscle retention, Xtend Ripped supports long-term fat loss while enhancing workout performance.
This formula also includes L-carnitine and CLA, two ingredients known for their fat-burning properties.
L-carnitine helps transport fatty acids into the mitochondria, where they are converted into energy, reducing fat storage and improving endurance.
CLA supports metabolism and assists in regulating body fat levels, making it easier to achieve a leaner physique.
Xtend Ripped also contains electrolytes to promote hydration, which is crucial for performance and recovery.
Whether taken before, during, or after a workout, this supplement helps fuel training sessions, enhance recovery, and support muscle growth while promoting efficient fat burning.
- Preserves muscle mass while promoting fat loss
- Enhances endurance and hydration for improved performance
- Supports fat metabolism by increasing energy utilization
Last update on 2025-04-19 / This article includes affiliate links/Images via Amazon Product Advertising API. I may earn commissions on purchases made through these links.
8.) BIOHM Super Greens with Probiotics
BIOHM Super Greens with Probiotics is a nutrient-dense superfood supplement designed to improve gut microbiome balance, enhance digestion, and optimize metabolic efficiency.
A healthy gut plays a critical role in body composition by supporting nutrient absorption, regulating inflammation, and influencing energy metabolism, all of which are essential for fat loss and muscle growth.
This formula combines probiotics, prebiotic fiber, and digestive enzymes to create a digestive environment that maximizes nutrient utilization.
Probiotics introduce beneficial bacteria that help maintain gut balance, while prebiotics serve as fuel to encourage the growth and activity of these bacteria.
This improves digestion, supports immune function, and enhances the body’s ability to metabolize fat.
The fiber content promotes regular digestion, helping to prevent bloating and sluggish metabolism, while digestive enzymes assist in breaking down food efficiently.
This ensures that essential nutrients such as protein and amino acids are fully absorbed, fueling muscle recovery and growth while supporting fat metabolism.
By improving digestion, reducing inflammation, and enhancing nutrient absorption, BIOHM Super Greens helps create an optimal internal environment for sustaining muscle development and efficient fat burning.
Its blend of greens, probiotics, and enzymes makes it a valuable addition to any diet focused on long-term weight management and muscle retention.
- Supports digestion and gut health for efficient nutrient absorption
- Reduces bloating and inflammation for better metabolic function
- Enhances nutrient utilization, promoting muscle growth and fat loss
Last update on 2025-04-19 / This article includes affiliate links/Images via Amazon Product Advertising API. I may earn commissions on purchases made through these links.
9.) Sports Research Vitamin D3 & K2
Sports Research Vitamin D3 & K2 is an essential supplement that optimizes hormone balance, supports fat metabolism, and enhances overall metabolic efficiency.
Proper hormonal function is a key factor in achieving a lean physique, as it regulates energy levels, muscle recovery, and fat storage.
Vitamin D plays a crucial role in maintaining optimal hormone levels, including those that influence fat loss and muscle growth.
Many individuals have insufficient vitamin D levels, which can contribute to a sluggish metabolism, increased fat accumulation, and decreased energy production.
By ensuring adequate vitamin D intake, vitamin D supplements help support the body’s natural fat-burning processes while promoting steady energy levels throughout the day.
Vitamin K2 works synergistically with vitamin D to enhance calcium metabolism, ensuring that calcium is effectively used by the body rather than accumulating in arteries.
This not only supports cardiovascular health but also contributes to overall metabolic efficiency.
Additionally, both vitamin D3 and K2 improve insulin sensitivity, which is essential for regulating blood sugar levels, preventing fat storage, and optimizing muscle recovery.
By improving hormone function, increasing energy levels, and supporting metabolic balance, Sports Research Vitamin D3 & K2 helps create the ideal conditions for sustainable fat loss and muscle retention.
It is a foundational supplement for those looking to optimize body composition while maintaining overall health.
- Supports hormonal balance to enhance fat metabolism and muscle growth
- Improves energy levels and immune function for better recovery and performance
- Regulates insulin sensitivity to prevent excess fat storage and promote lean muscle development
Last update on 2025-04-20 / This article includes affiliate links/Images via Amazon Product Advertising API. I may earn commissions on purchases made through these links.
10.) Optimum Nutrition Gold Standard Whey Protein
Optimum Nutrition Gold Standard Whey Protein is a high-quality protein powder supplement designed to optimize muscle growth, enhance recovery, and support fat loss.
Protein intake is essential for improving body composition, as it helps preserve lean muscle mass while promoting fat metabolism.
Each serving provides 24 grams of fast-digesting whey protein, delivering all essential amino acids necessary for muscle repair and development.
Maintaining lean muscle is crucial for sustaining a higher metabolic rate, as muscle tissue burns more calories at rest than fat.
By consuming an adequate amount of protein, the body remains in an anabolic state, reducing muscle breakdown and promoting recovery.
The fast-absorbing nature of whey protein makes it particularly effective post-workout, ensuring that muscles receive the nutrients needed for repair and growth.
Additionally, protein plays a key role in appetite regulation, helping to promote satiety and prevent overeating, which supports long-term fat loss.
Optimum Nutrition’s formula is low in fat and sugar, providing a clean source of protein without unnecessary additives.
Whether used for muscle-building purposes or to maintain lean mass during a fat-loss phase, this supplement is a reliable and effective option for improving overall body composition.
- Preserves muscle mass while supporting fat metabolism
- Regulates appetite and promotes fullness, reducing overeating
- Provides fast-digesting protein for post-workout recovery and muscle repair
Last update on 2025-04-19 / This article includes affiliate links/Images via Amazon Product Advertising API. I may earn commissions on purchases made through these links.
